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 Holly Hargreaves posted on Wednesday, June 05, 2013 - 8:14 am
Good Morning,

May I be directed to resources regarding information on the minimum sample size required for Latent Class Analysis (LCA) as well as information on conducting a power analysis for LCA? I have completed coursework in structural equation modeling and attended Dr. Muthen's training at the 2013 APS Convention however I have only recently began studying LCA and conducting analyses on MPlus therefore any information and/or insight would be greatly appreciated. Thank you very much.

Kind Regards,

 Bengt O. Muthen posted on Wednesday, June 05, 2013 - 10:19 am
One useful starting point is:

Nylund, K.L., Asparouhov, T., & Muthén, B. (2007). Deciding on the number of classes in latent class analysis and growth mixture modeling. A Monte Carlo simulation study. Structural Equation Modeling, 14, 535-569.

Others may have other suggestions.
 Holly Hargreaves posted on Wednesday, June 05, 2013 - 11:25 am
Thank you very much Dr. Muthen. It is my understanding that LCA is not advised with sample sizes smaller than n=100. Is n=117 sufficient in some cases? Any insight as to general rules of thumb would also be greatly appreciated. I sincerely appreciate your time.
 Bengt O. Muthen posted on Wednesday, June 05, 2013 - 1:23 pm
It all depends on how well the classes are separated. With binary outcomes that means how different the thresholds (conditional item probabilities) are. I have done successful mixture modeling with only 30 subjects, so I wouldn't rule out using LCA for 117 subjects. General rules of thumb are not worth much for mixtures because results depend so much on the specifics of your situation. That's why we suggest Monte Carlo studies - see the UG chapter 12. See also the Monte Carlo article:

Muthén, L.K. & Muthén, B.O. (2002). How to use a Monte Carlo study to decide on sample size and determine power. Structural Equation Modeling, 4, 599-620.

with scripts on our website.
 Holly Hargreaves posted on Wednesday, June 05, 2013 - 1:28 pm
Thank you again, I will ensure to read the chapter and article. Is the chapter referenced above on your website as well?
 Linda K. Muthen posted on Wednesday, June 05, 2013 - 1:32 pm
Both items are on the website.
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