

Proportion of total effect mediated 

Message/Author 

Jon Heron posted on Wednesday, August 03, 2011  8:25 am



Hi Bengt/Linda, I have a simple mediation model in which X, M and Y are all binary. I am interested in the proportion of the effect from X to Y which is mediated through M. My Mplus model: MODEL: Y on X M; M on X; model indirect: Y IND X; gives a total effect of 0.386 and total indirect of 0.149, so I get a proportion of 0.149/0.386 = 38.6% As I am aware of the issues regarding mediation involving binary variables, I have been attempting to replicate these figures using Stata (binary_mediation function) and also using the excel spreadsheet from Nathaniel Herr's website (http://nrherr.bol.ucla.edu/Mediation/logmed.html). These are based on the same approach and both report that the proportion mediated is 22.9% Now the stata/Herr approaches scale the a/b/c/c' parameters by ratios of SD's such that the indirect effect, and hence the proportion mediated, are derived from figures that bear little resemblance to the original regression models. In contrast, the total effect in my Mplus analysis is clearly just the cpath were I just to regress Y on X. It seems that Mplus has a slightly different scaling routine such that the regression equation for M on X maintains it's residual variance of 1, whilst the equation for Y is scaled  presumably to render the parameter estimates comparable. 

Jon Heron posted on Wednesday, August 03, 2011  8:26 am



Is this slightly different approach enough to explain this rather large discrepancy? thanks, Jon 


The difference is likely because in Mplus m is treated as m*, the latent response variable underlying m, both as a dependent and independent variable. 

Jon Heron posted on Thursday, August 04, 2011  5:37 am



Oh I see, thanks that makes sense Jon 


Good afternoon Dr. Bengt and Linda Muthen, I wanted to verify my understanding from this post. In order to calculate the percentage of the effect that is mediated by a specified model, the standardized "total indirect estimate" should be dived by the standardized "total estimate," correct? Also, are there handouts that discuss the significance levels of the total effects versus total indirect effects? I would like to read up more on what this means. Thank you much for your time and any information that can be provided. Have a good weekend. 


This is a good general question for SEMNET. 


Thank you much. 

Back to top 

