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Cluster Randomized Trials |
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Hi! I am working on analyzing the data from a cluster randomized trials. A total of 14 schools participated -- 7 intervention and 7 control. The randomization was done in pairs of schools -- within each pair, one school was randomized to the intervention and the other to control. I was asked to run the analysis while preserving the "yolked" (i.e., randomization in pairs) structure of the design. How do I do this in Mplus? I coded the 7 pairs and used the CLUSTER command, but I am not sure it is correct. Do I need to calculate ICCs? How do I do this? Also, how do I get the standard deviation for the constructs measured in each of the schools? Thank you for your help! |
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Randomized pairs sounds like matched pairs randomization for which there are special analysis techniques (preserving the yolked design). Such analysis is not done in Mplus. It is different from a completely randomized design which Mplus would assume. |
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Lu posted on Thursday, May 31, 2018 - 6:26 pm
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Hi Dr. Muthen, Can Mplus be used to analyze cluster randomized controlled trial? I'm planning a cluster RCT study with 8 clinics and 30 participants from each clinic. 4 clinics will be assigned to intervention, and 4 clinics will be assigned to control. I have seen study protocols using Mplus to estimate power for similar design, but unsure how to set this up in Mplus in terms of clustering and ICC. Thanks very much! |
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Answered elsewhere. |
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