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I cannot fit a common factor GxE model with twins data (similar to Harden et al- MPLUS/genetics section of website). I am getting troubling estimates. U, which is the estimate of c' is large and negative. At the maximum of the moderator c will be negative (?). Moderator ranges from 0 to 1. f_t1 (v1); f_t2 (v2); new(a c e t u); v1=(a+t*covariate1)**2 + (c+u* covariate1)**2 +e**2; v2=(a+t*covariate2)**2 + (c+u* covariate2)**2 +e**2; mzc=(a+t* covariate1)*(a+t* covariate2) + (c+u* covariate1)*(c+u* covariate2); dzc=0.50*(a+t* covariate1)*(a+t* covariate2) + (c+u* covariate1)*(c+u*covariate2); F_T1 ON COVARIATE1 0.737 0.169 4.348 0.000 F_T2 ON COVARIATE2 0.737 0.169 4.348 0.000 New/Additional Parameters A -0.467 0.305 -1.532 0.125 C 0.731 0.217 3.370 0.001 E 0.615 0.039 15.747 0.000 T -0.116 0.441 -0.264 0.792 U -1.081 0.293 -3.690 0.000 Thanks! |
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Hi I try to fit a bivariate GxE model in Mplus, where the moderator not only features as a variable whose variance is decomposed but also as a contraint variable. I get the message: *** FATAL ERROR THIS PARAMETER RESTRICTION MODEL IS NOT AVAILABLE. i.e., this model cannot be fit in Mplus? thanks Sophie |
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Please send your output and license number to support@statmodel.com. |
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Erika Wolf posted on Tuesday, September 20, 2011 - 9:50 am
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I am trying to run a G by measured E ACE model. I get an error message that the computation could not be completed and that the correlation and residual correlation between A2 and A1 is 1.0. I tried ALGORITHM=EM AND set MCONVERGENCE to .01 but this did not help. Please advise. Model: [x x2] (1); x@0; x2@0; [z z2] (11); z (13); z2 (13); A1 BY x*.64 (3); A2 BY x2*.64 (3); C1 BY x@0 (4); C2 BY x2@0 (4); E1 BY x*.76 (5); E2 BY x2*.76 (5); [A1-E2@0]; A1-E2@1; X on z (12); X2 on z2(12); GXz |A1 XWITH z; GXz2|A2 XWITH z2; x on GXz (14); x2 ON GXz2 (14); a1 with a2@1; C1 WITH C2@1; e1 with e2@0; [I'm omitting the other ACE correlations @0 here to save space] MODEL DZ: A1 WITH A2@.5; |
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Please send the output and your license number to support@statmodel.com. |
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