I ran 2 models in which I am looking at the change between anxiety and depression symptoms in the context of a treatment study. I ran the model twice where the flow of change goes from anxiety and depression (effects from anxiety at post to depression at post; and anxiety at follow-up to depression at follow-up and then vice-versa). I get a negative sign from anxiety at post to depression at follow-up and from depression at post to anxiety at follow-up. Both lagged effects are negative in sign. I am confussed because the contemporeneous effects from anx to dep and dep to anx at post and follow-up are positive in sign and the lagged effects negative. Does the negative sign for the lagged effects makes sense?? I pasted part of the output with one of the models wihout covariates. RCMASFU ON RCMAS 0.118 0.168 CDI 0.142 0.095 RCMASPO 0.401 0.000 CDIPO 0.047 0.688
I should say that I am not sure of the interpretation, not the actual syntax or running the data.
I don't know if the negative sign means that lower levels of anxiety at post (RCMASPO = -.27, p < .001)) predict higher or more changes in depression from post to follow-up (CDIFU ON CDIPO) or if It is actually the opposite where I would say that changes in anxiety from pre to post (RCMASPO ON RCMAS) work their way up to predict changes in depression from post to follow-up, but this will actually be less (more change in anxiety, less change in depression). The former makes sense, but not the latter interpretation, hence why I am not sure what to make of the negative sign.